node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SHE55444.1 | SHE55929.1 | SAMN05444320_101404 | SAMN05444320_101419 | Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. | Fructose-bisphosphate aldolase, class II. | 0.865 |
SHE55444.1 | SHE98363.1 | SAMN05444320_101404 | SAMN05444320_102166 | Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. | Ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. | 0.552 |
SHE55444.1 | SHE99336.1 | SAMN05444320_101404 | SAMN05444320_102193 | Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. | Glyceraldehyde 3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. | 0.993 |
SHE55444.1 | SHE99741.1 | SAMN05444320_101404 | SAMN05444320_102206 | Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. | Glucose-6-phosphate isomerase; Belongs to the GPI family. | 0.962 |
SHE55444.1 | SHE99809.1 | SAMN05444320_101404 | SAMN05444320_102208 | Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. | Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. | 0.951 |
SHE55444.1 | SHG32402.1 | SAMN05444320_101404 | SAMN05444320_10825 | Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. | Fructose-1,6-bisphosphatase II. | 0.925 |
SHE55444.1 | SHG67859.1 | SAMN05444320_101404 | SAMN05444320_11239 | Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. | Tagatose 6-phosphate kinase; Belongs to the carbohydrate kinase PfkB family. | 0.898 |
SHE55444.1 | pfp | SAMN05444320_101404 | SAMN05444320_103515 | Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. | 6-phosphofructokinase 1; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. | 0.974 |
SHE55444.1 | tal | SAMN05444320_101404 | SAMN05444320_102207 | Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. | Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 2 subfamily. | 0.958 |
SHE55929.1 | SHE55444.1 | SAMN05444320_101419 | SAMN05444320_101404 | Fructose-bisphosphate aldolase, class II. | Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. | 0.865 |
SHE55929.1 | SHE99336.1 | SAMN05444320_101419 | SAMN05444320_102193 | Fructose-bisphosphate aldolase, class II. | Glyceraldehyde 3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. | 0.976 |
SHE55929.1 | SHE99741.1 | SAMN05444320_101419 | SAMN05444320_102206 | Fructose-bisphosphate aldolase, class II. | Glucose-6-phosphate isomerase; Belongs to the GPI family. | 0.962 |
SHE55929.1 | SHE99809.1 | SAMN05444320_101419 | SAMN05444320_102208 | Fructose-bisphosphate aldolase, class II. | Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. | 0.925 |
SHE55929.1 | SHG32402.1 | SAMN05444320_101419 | SAMN05444320_10825 | Fructose-bisphosphate aldolase, class II. | Fructose-1,6-bisphosphatase II. | 0.875 |
SHE55929.1 | SHG67859.1 | SAMN05444320_101419 | SAMN05444320_11239 | Fructose-bisphosphate aldolase, class II. | Tagatose 6-phosphate kinase; Belongs to the carbohydrate kinase PfkB family. | 0.984 |
SHE55929.1 | pfp | SAMN05444320_101419 | SAMN05444320_103515 | Fructose-bisphosphate aldolase, class II. | 6-phosphofructokinase 1; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. | 0.897 |
SHE55929.1 | tal | SAMN05444320_101419 | SAMN05444320_102207 | Fructose-bisphosphate aldolase, class II. | Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 2 subfamily. | 0.917 |
SHE98363.1 | SHE55444.1 | SAMN05444320_102166 | SAMN05444320_101404 | Ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. | Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. | 0.552 |
SHE98363.1 | SHE99336.1 | SAMN05444320_102166 | SAMN05444320_102193 | Ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. | Glyceraldehyde 3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. | 0.884 |
SHE98363.1 | SHE99741.1 | SAMN05444320_102166 | SAMN05444320_102206 | Ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. | Glucose-6-phosphate isomerase; Belongs to the GPI family. | 0.650 |