Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
AIS61701.1Universal stress protein UspA; Derived by automated computational analysis using gene prediction method: Protein Homology. (143 aa)    
Predicted Functional Partners:
AIS62812.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.615
AIS61700.1
Cell surface protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.539
AIS63148.1
TPR repeat-containing protein ypiA; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.476
AIS62831.1
General stress protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.470
ezrA
Septation ring formation regulator EzrA; Negative regulator of FtsZ ring formation; modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization; Belongs to the EzrA family.
  
     0.457
deoA
Thymidine phosphorylase; Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
    0.435
AIS61324.1
Cysteine methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
  
 0.426
AIS62250.1
Cysteine methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
   
  
 0.426
AIS63466.1
Cysteine methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
  
 0.426
hpf
Sigma-54 modulation protein; Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.
   
  
 0.403
Your Current Organism:
Listeria ivanovii
NCBI taxonomy Id: 202752
Other names: ATCC 49954, CCUG 36672, CIP 103466, CLIP 12229, DSM 12491, L. ivanovii subsp. londoniensis, Listeria ivanovii subsp. londoniensis, NCTC 12701
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