Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AIS62650.1hydroxymethylglutaryl-CoA synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (388 aa)    
Predicted Functional Partners:
AIS62649.1
acetyl-CoA acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family.
 
 0.999
AIS62085.1
3-hydroxy-3-methylglutaryl-CoA reductase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the HMG-CoA reductase family.
 
 0.997
AIS61268.1
Diphosphomevalonate decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.968
AIS63957.1
Mevalonate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.952
AIS63958.1
Phosphomevalonate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.950
fni
Isopentenyl-diphosphate delta-isomerase; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
 
 
 0.926
AIS62798.1
Citrate synthase; Catalyzes the formation of citrate from acetyl-CoA and oxaloacetate; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.856
AIS62088.1
Pyruvate-flavodoxin oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.850
AIS62305.1
Dihydrolipoamide acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.850
AIS62631.1
Formate acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
  0.843
Your Current Organism:
Listeria ivanovii
NCBI taxonomy Id: 202752
Other names: ATCC 49954, CCUG 36672, CIP 103466, CLIP 12229, DSM 12491, L. ivanovii subsp. londoniensis, Listeria ivanovii subsp. londoniensis, NCTC 12701
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