Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AIS62653.1Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (345 aa)    
Predicted Functional Partners:
murB
UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation.
       0.686
AIS64016.1
Phosphodiesterase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.594
AIS62652.1
MFS transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.563
AIS62651.1
Transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.510
AIS62201.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.464
mprF
lysyl-tRNA synthetase; Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms.
 
   
 0.460
AIS61746.1
Peptide transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.445
AIS63720.1
Lipoprotein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.434
AIS62655.1
Glycine/betaine ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.429
AIS62656.1
Glycine/betaine ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.429
Your Current Organism:
Listeria ivanovii
NCBI taxonomy Id: 202752
Other names: ATCC 49954, CCUG 36672, CIP 103466, CLIP 12229, DSM 12491, L. ivanovii subsp. londoniensis, Listeria ivanovii subsp. londoniensis, NCTC 12701
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