Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AIS63699.1Glycosyl transferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (342 aa)    
Predicted Functional Partners:
AIS63700.1
1,2-diacylglycerol 3-glucosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.991
mprF-2
Membrane protein; Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms.
 
  
 0.916
AIS63989.1
Membrane sulfatase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the LTA synthase family.
    
 0.856
AIS62330.1
UTP--glucose-1-phosphate uridylyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.745
AIS62180.1
Glycerol phosphate lipoteichoic acid synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the LTA synthase family.
    
 0.728
dltA
Alanine-phosphoribitol ligase; Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D- alanyl carrier protein (Dcp) DltC. In an ATP-dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall. Belongs to the ATP-dependent A [...]
  
  
 0.722
AIS62334.1
CDP-glycerol:glycerophosphate glycerophosphotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.686
AIS62229.1
Alanine transporter; Could be involved in the transport of activated D-alanine through the membrane.
  
 
 0.671
AIS62227.1
DltD; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.653
AIS63357.1
Cyclomaltodextrinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glycosyl hydrolase 13 family.
    
 0.647
Your Current Organism:
Listeria ivanovii
NCBI taxonomy Id: 202752
Other names: ATCC 49954, CCUG 36672, CIP 103466, CLIP 12229, DSM 12491, L. ivanovii subsp. londoniensis, Listeria ivanovii subsp. londoniensis, NCTC 12701
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