Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AIS63906.1Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (248 aa)    
Predicted Functional Partners:
dltA
Alanine-phosphoribitol ligase; Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D- alanyl carrier protein (Dcp) DltC. In an ATP-dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall. Belongs to the ATP-dependent A [...]
 
 0.935
AIS62088.1
Pyruvate-flavodoxin oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.865
AIS62966.1
Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.811
AIS63907.1
Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.773
AIS62801.1
Pyruvate kinase; Catalyzes the formation of phosphoenolpyruvate from pyruvate; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.727
AIS61282.1
PTS beta-glucoside transporter subunit IIABC; Phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.701
AIS61387.1
PTS sugar transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.701
AIS61588.1
PTS beta-glucoside transporter subunit IIA; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.701
AIS61785.1
PTS beta-glucoside transporter subunit IIABC; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.701
AIS61786.1
Sugar permease; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.701
Your Current Organism:
Listeria ivanovii
NCBI taxonomy Id: 202752
Other names: ATCC 49954, CCUG 36672, CIP 103466, CLIP 12229, DSM 12491, L. ivanovii subsp. londoniensis, Listeria ivanovii subsp. londoniensis, NCTC 12701
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