Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ccmH_1Cytochrome C biosynthesis protein; Possible subunit of a heme lyase. (130 aa)    
Predicted Functional Partners:
ccmF_1
Cytochrome C biogenesis protein CcmF; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.983
dsbE_1
Dihydroneopterin aldolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.965
ccmF_4
Cytochrome c-type biogenesis protein; required for the transfer of heme to apocytochrome c; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.945
ACEE_00940
Cytochrome C biogenesis protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.926
ccmE_1
Cytochrome C biogenesis protein CcmE; Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.
 
  
 0.872
ccmC
Heme ABC transporter permease; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmC/CycZ/HelC family.
 
  
 0.864
dsbE_2
Thiol:disulfide interchange protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.855
ccmB
Heme ABC transporter permease; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmB/CycW/HelB family.
 
   
 0.848
ccmA_1
Heme ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.842
ccmH_2
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.785
Your Current Organism:
Actinobacillus equuli
NCBI taxonomy Id: 202947
Other names: A. equuli subsp. equuli, Actinobacillus equuli subsp. equuli
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