Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
dnaB2_2DNA helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. (487 aa)    
Predicted Functional Partners:
dnaG
DNA primase; Synthesizes RNA primers at the replication forks; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.915
ACEE_04720
DNA helicase; Unwinds double stranded DNA; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 
0.907
dnaA
Chromosomal replication initiation protein; Binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.842
nrdR_2
NrdR family transcriptional regulator; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family.
     
 0.781
ACEE_03490
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.773
ACEE_05855
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
   0.672
dnaE
DNA polymerase III subunit alpha; Catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time; main replicative polymerase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.657
rpoA
DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
 
  
 0.647
ftsI_2
Cell division protein FtsI; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   
 0.626
polA_6
DNA polymerase I; Has 3'-5' exonuclease, 5'-3' exonuclease and 5'-3'polymerase activities, primarily functions to fill gaps during DNA replication and repair; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.597
Your Current Organism:
Actinobacillus equuli
NCBI taxonomy Id: 202947
Other names: A. equuli subsp. equuli, Actinobacillus equuli subsp. equuli
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