STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
potCSpermidine/putrescine ABC transporter permease; Can transport spermidine and putrescine but affinity is higher for spermidine; forms a complex of PotA2BCD; PotC is a membrane component; Derived by automated computational analysis using gene prediction method: Protein Homology. (246 aa)    
Predicted Functional Partners:
potB_1
Spermidine/putrescine ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
0.999
potD2_1
Spermidine/putrescine ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.998
potA
Putrescine/spermidine ABC transporter ATPase; Functions together with PotBCD (A2BCD) in ATP-dependent polyamine transport; PotA is the membrane-associated ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ABC transporter superfamily.
 
 
 0.998
potD_3
Spermidine/putrescine ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.998
fbpC
Ferric transporter ATP-binding subunit; Part of the ABC transporter complex FbpABC involved in Fe(3+) ions import; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.848
murB
UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation.
  
  
 0.576
folK
7, 8-dihydro-6-hydroxymethylpterin-pyrophosphokinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.509
ruvA
Holliday junction ATP-dependent DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.
       0.484
ruvB
ATP-dependent DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.
       0.459
cysA_4
Sulfate ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.442
Your Current Organism:
Actinobacillus equuli
NCBI taxonomy Id: 202947
Other names: A. equuli subsp. equuli, Actinobacillus equuli subsp. equuli
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