proC protein (Actinobacillus equuli) - STRING interaction network

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proC

Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (273 aa)

Predicted Functional Partners:

putA_5

0.944

proA

0.801

proB_2

0.793

hcaT

0.789

citC

0.773

ACEE_11460

0.555

argD2_2

0.481

lysA_2

0.454

ACEE_03205

0.433

thrA

0.413

Your Current Organism:

Actinobacillus equuli

NCBI taxonomy Id: 202947
Other names: A. equuli subsp. equuli, Actinobacillus equuli subsp. equuli

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACEE_03205	proA	ACEE_03205	ACEE_07800	Recombinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family.	0.414
ACEE_03205	proB_2	ACEE_03205	ACEE_05535	Recombinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Gamma-glutamyl kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.	0.407
ACEE_03205	proC	ACEE_03205	ACEE_06515	Recombinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.	0.433
ACEE_11460	proC	ACEE_11460	ACEE_06515	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.	0.555
argD2_2	lysA_2	ACEE_01125	ACEE_10360	Acetylornithine aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Diaminopimelate decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.432
argD2_2	proC	ACEE_01125	ACEE_06515	Acetylornithine aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.	0.481
citC	hcaT	ACEE_06525	ACEE_06520	[citrate [pro-3S]-lyase] ligase; Derived by automated computational analysis using gene prediction method: Protein Homology.	MFS transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.773
citC	proC	ACEE_06525	ACEE_06515	[citrate [pro-3S]-lyase] ligase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.	0.773
hcaT	citC	ACEE_06520	ACEE_06525	MFS transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.	[citrate [pro-3S]-lyase] ligase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.773
hcaT	proC	ACEE_06520	ACEE_06515	MFS transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.	Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.	0.789
lysA_2	argD2_2	ACEE_10360	ACEE_01125	Diaminopimelate decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Acetylornithine aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.432
lysA_2	proC	ACEE_10360	ACEE_06515	Diaminopimelate decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.	0.454
lysA_2	thrA	ACEE_10360	ACEE_01155	Diaminopimelate decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Aspartate kinase; Multifunctional homotetrameric enzyme that catalyzes the phosphorylation of aspartate to form aspartyl-4-phosphate as well as conversion of aspartate semialdehyde to homoserine; functions in a number of amino acid biosynthetic pathways; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aspartokinase family.	0.423
proA	ACEE_03205	ACEE_07800	ACEE_03205	Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family.	Recombinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.414
proA	proB_2	ACEE_07800	ACEE_05535	Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family.	Gamma-glutamyl kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.	0.999
proA	proC	ACEE_07800	ACEE_06515	Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family.	Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.	0.801
proA	putA_5	ACEE_07800	ACEE_06810	Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family.	Proline dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.929
proA	thrA	ACEE_07800	ACEE_01155	Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family.	Aspartate kinase; Multifunctional homotetrameric enzyme that catalyzes the phosphorylation of aspartate to form aspartyl-4-phosphate as well as conversion of aspartate semialdehyde to homoserine; functions in a number of amino acid biosynthetic pathways; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aspartokinase family.	0.438
proB_2	ACEE_03205	ACEE_05535	ACEE_03205	Gamma-glutamyl kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.	Recombinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.407
proB_2	proA	ACEE_05535	ACEE_07800	Gamma-glutamyl kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.	Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family.	0.999