node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
F990_00699 | F990_01320 | GCA_000759995_02098 | GCA_000759995_02658 | Unannotated protein; Belongs to the HSP15 family. | Unannotated protein; Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress; Belongs to the HSP33 family. | 0.835 |
F990_00699 | dnaJ | GCA_000759995_02098 | GCA_000759995_01517 | Unannotated protein; Belongs to the HSP15 family. | Unannotated protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK [...] | 0.467 |
F990_00699 | grpE | GCA_000759995_02098 | GCA_000759995_00298 | Unannotated protein; Belongs to the HSP15 family. | Unannotated protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-depe [...] | 0.467 |
F990_01316 | F990_01317 | GCA_000759995_02662 | GCA_000759995_02661 | Unannotated protein. | Unannotated protein. | 0.980 |
F990_01316 | F990_01320 | GCA_000759995_02662 | GCA_000759995_02658 | Unannotated protein. | Unannotated protein; Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress; Belongs to the HSP33 family. | 0.586 |
F990_01316 | priA | GCA_000759995_02662 | GCA_000759995_02660 | Unannotated protein. | Unannotated protein; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. | 0.606 |
F990_01317 | F990_01316 | GCA_000759995_02661 | GCA_000759995_02662 | Unannotated protein. | Unannotated protein. | 0.980 |
F990_01317 | F990_01319 | GCA_000759995_02661 | GCA_000759995_02659 | Unannotated protein. | Unannotated protein; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. | 0.628 |
F990_01317 | F990_01320 | GCA_000759995_02661 | GCA_000759995_02658 | Unannotated protein. | Unannotated protein; Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress; Belongs to the HSP33 family. | 0.589 |
F990_01317 | priA | GCA_000759995_02661 | GCA_000759995_02660 | Unannotated protein. | Unannotated protein; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. | 0.743 |
F990_01319 | F990_01317 | GCA_000759995_02659 | GCA_000759995_02661 | Unannotated protein; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. | Unannotated protein. | 0.628 |
F990_01319 | F990_01320 | GCA_000759995_02659 | GCA_000759995_02658 | Unannotated protein; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. | Unannotated protein; Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress; Belongs to the HSP33 family. | 0.731 |
F990_01319 | F990_01321 | GCA_000759995_02659 | GCA_000759995_02657 | Unannotated protein; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. | Unannotated protein. | 0.505 |
F990_01319 | priA | GCA_000759995_02659 | GCA_000759995_02660 | Unannotated protein; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. | Unannotated protein; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. | 0.684 |
F990_01320 | F990_00699 | GCA_000759995_02658 | GCA_000759995_02098 | Unannotated protein; Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress; Belongs to the HSP33 family. | Unannotated protein; Belongs to the HSP15 family. | 0.835 |
F990_01320 | F990_01316 | GCA_000759995_02658 | GCA_000759995_02662 | Unannotated protein; Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress; Belongs to the HSP33 family. | Unannotated protein. | 0.586 |
F990_01320 | F990_01317 | GCA_000759995_02658 | GCA_000759995_02661 | Unannotated protein; Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress; Belongs to the HSP33 family. | Unannotated protein. | 0.589 |
F990_01320 | F990_01319 | GCA_000759995_02658 | GCA_000759995_02659 | Unannotated protein; Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress; Belongs to the HSP33 family. | Unannotated protein; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. | 0.731 |
F990_01320 | F990_01321 | GCA_000759995_02658 | GCA_000759995_02657 | Unannotated protein; Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress; Belongs to the HSP33 family. | Unannotated protein. | 0.582 |
F990_01320 | dnaJ | GCA_000759995_02658 | GCA_000759995_01517 | Unannotated protein; Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress; Belongs to the HSP33 family. | Unannotated protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK [...] | 0.472 |