STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sirAIn Escherichia coli the protein UvrY is part of a two-component system along with BarA that is needed for efficient switching between glycolytic and gluconeogenic carbon sources possibly by regulating the Csr system; in Salmonella SirA and BarA regulate virulence gene expression also via the Csr system; Derived by automated computational analysis using gene prediction method: Protein Homology. (211 aa)    
Predicted Functional Partners:
OFE44522.1
Hybrid sensor histidine kinase/response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.999
OFE43270.1
ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.876
OFE43185.1
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
  0.864
OFE44506.1
Two-component sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.818
OFE42999.1
Hybrid sensor histidine kinase/response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.809
OFE44858.1
Hybrid sensor histidine kinase/response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.801
OFE43186.1
Sigma-54-dependent Fis family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.776
OFE43652.1
GGDEF domain-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.745
OFE43183.1
D-alanyl-D-alanine endopeptidase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S11 family.
       0.694
OFE44436.1
Diguanylate phosphodiesterase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.688
Your Current Organism:
Acinetobacter towneri
NCBI taxonomy Id: 202956
Other names: A. towneri, Acinetobacter towneri Carr et al. 2003, CIP 107472, DSM 14962, strain AB1110
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