STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Cthe_0015PFAM: alpha-L-arabinofuranosidase B; Dockerin type 1; glycoside hydrolase family 43; KEGG: bsu:BSU39330 arabinan endo-1,5-alpha-L-arabinosidase. (707 aa)    
Predicted Functional Partners:
Cthe_2548
alpha-L-arabinofuranosidase domain protein; Involved in the degradation of arabinan and is a key enzyme in the complete degradation of the plant cell wall. Catalyzes the cleavage of terminal alpha-(1->5)-arabinofuranosyl bonds in small oligosaccharides as alpha-(1->5)-linked arabinobiose/arabinotriose, but does not display significant activity against linear non-substituted arabinan. It is also highly efficient in the cleavage of alpha-(1->3)- linked arabinoside of xylobiose and of the alpha-(1->3)-linked arabinoside decorations of polymeric wheat arabinoxylan. It exhibits very low act [...]
 
  
 0.795
Cthe_1911
KEGG: cce:Ccel_1656 carbohydrate binding family 6; PFAM: Carbohydrate binding family 6; S-layer domain-containing protein; SMART: cellulose binding type IV.
  
     0.577
Cthe_1257
Carbohydrate-binding CenC domain protein; KEGG: csc:Csac_1076 glycoside hydrolase family protein; PFAM: Carbohydrate-binding CenC domain protein; type 3a cellulose-binding domain protein; SMART: von Willebrand factor type A.
  
    0.534
Cthe_2809
Glucan endo-1,3-beta-D-glucosidase; KEGG: pjd:Pjdr2_0824 glycoside hydrolase family 16; PFAM: glycoside hydrolase family 16; Carbohydrate-binding CenC domain protein; S-layer domain-containing protein.
  
 0.514
rsgI6
Glycoside hydrolase family 10; Anti-sigma factor for SigI6. Negatively regulates SigI6 activity through direct interaction. Binding of the polysaccharide substrate to the extracellular C-terminal sensing domain of RsgI6 may induce a conformational change in its N-terminal cytoplasmic region, leading to the release and activation of SigI6 (By similarity). Binds to and hydrolyzes insoluble and soluble xylan substrates. Has low enzymatic activity ; In the C-terminal section; belongs to the glycosyl hydrolase 10 (cellulase F) family.
 
  
 0.494
Cthe_0912
Glycoside hydrolase family 10; KEGG: cpy:Cphy_0624 endo-1,4-beta-xylanase; PFAM: glycoside hydrolase family 10; Carbohydrate-binding CenC domain protein; Dockerin type 1; esterase; SMART: glycoside hydrolase family 10.
 
  
0.448
xynZ
Glycoside hydrolase family 10; KEGG: cce:Ccel_1232 carbohydrate binding family 6; PFAM: glycoside hydrolase family 10; Carbohydrate binding family 6; esterase; Dockerin type 1; SMART: glycoside hydrolase family 10; cellulose binding type IV.
 
   
0.441
rsgI3
PA14 domain protein; Anti-sigma factor for SigI3. Negatively regulates SigI3 activity through direct interaction. Binding of the polysaccharide substrate to the extracellular C-terminal sensing domain of RsgI3 may induce a conformational change in its N-terminal cytoplasmic region, leading to the release and activation of SigI3.
  
  
 0.436
Cthe_3063
Cephalosporin-C deacetylase; KEGG: bsu:BSU03180 S-deacylase; PFAM: Acetyl xylan esterase.
 
   
 0.428
celE
Glycoside hydrolase family 5; Multifunctional enzyme involved in the degradation of plant cell wall polysaccharides. Displays endoglucanase activity against carboxymethyl cellulose (CMC) and barley beta-glucan. Also catalyzes the deacetylation of acetylated birchwood xylan and glucomannan, with a preference for the latter, and of the synthetic substrate 4-nitrophenyl acetate (4-NPAc) ; In the C-terminal section; belongs to the carbohydrate esterase 2 (CE2) family.
 
   
0.426
Your Current Organism:
Hungateiclostridium thermocellum
NCBI taxonomy Id: 203119
Other names: Clostridium thermocellum ATCC 27405, H. thermocellum ATCC 27405, Hungateiclostridium thermocellum ATCC 27405, Ruminiclostridium thermocellum ATCC 27405
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