STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gpmIPhosphoglycerate mutase, 2,3-bisphosphoglycerate-independent; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (511 aa)    
Predicted Functional Partners:
pgk
KEGG: cce:Ccel_2260 phosphoglycerate kinase; PFAM: phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family.
  
 
 0.994
eno
Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
  
 0.987
Cthe_1435
PFAM: Phosphoglycerate mutase; KEGG: seu:SEQ_2102 phosphoglycerate mutase family protein.
     
 0.956
Cthe_1292
TIGRFAM: proposed homoserine kinase; phosphonopyruvate decarboxylase-related protein; KEGG: cce:Ccel_2140 proposed homoserine kinase; PFAM: 2,3-bisphosphoglycerate-independent phosphoglycerate mutase; metalloenzyme domain protein.
  
 
 0.951
Cthe_2087
PFAM: metalloenzyme domain protein; KEGG: cce:Ccel_0175 metalloenzyme domain protein.
  
 
 
0.927
Cthe_0349
TIGRFAM: fructose-1,6-bisphosphate aldolase, class II; ketose-bisphosphate aldolase; KEGG: cce:Ccel_2222 fructose-1,6-bisphosphate aldolase, class II; PFAM: ketose-bisphosphate aldolase class-II.
   
 
 0.926
Cthe_1592
TIGRFAM: glycerate kinase; KEGG: tde:TDE0208 glycerate kinase; PFAM: glycerate kinase; Belongs to the glycerate kinase type-1 family.
     
 0.909
Cthe_3035
PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; amino acid-binding ACT domain protein; KEGG: ppd:Ppro_0734 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding.
    
 0.908
pgi
KEGG: cce:Ccel_1445 phosphoglucose isomerase (PGI); PFAM: phosphoglucose isomerase (PGI); Belongs to the GPI family.
  
 
 0.898
tpiA
Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
  
 
 0.892
Your Current Organism:
Hungateiclostridium thermocellum
NCBI taxonomy Id: 203119
Other names: Clostridium thermocellum ATCC 27405, H. thermocellum ATCC 27405, Hungateiclostridium thermocellum ATCC 27405, Ruminiclostridium thermocellum ATCC 27405
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