STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Cthe_0413PFAM: glycoside hydrolase family 9; Carbohydrate-binding CenC domain protein; type 3a cellulose-binding domain protein; Dockerin type 1; KEGG: cce:Ccel_0732 glycoside hydrolase family 9; Belongs to the glycosyl hydrolase 9 (cellulase E) family. (1224 aa)    
Predicted Functional Partners:
Cthe_0275
PFAM: glycosyltransferase 36; carbohydrate binding; glycosyltransferase 36 associated; KEGG: cce:Ccel_2109 glycosyltransferase 36.
  
  
  0.752
Cthe_2989
PFAM: glycosyltransferase 36; KEGG: tnp:Tnap_0603 glycosyltransferase 36.
  
  
  0.726
bglB
PFAM: glycoside hydrolase family 3 domain protein; KEGG: ttr:Tter_0181 glycoside hydrolase family 3 domain protein; Belongs to the glycosyl hydrolase 3 family.
   
 
 0.688
rsgI6
Glycoside hydrolase family 10; Anti-sigma factor for SigI6. Negatively regulates SigI6 activity through direct interaction. Binding of the polysaccharide substrate to the extracellular C-terminal sensing domain of RsgI6 may induce a conformational change in its N-terminal cytoplasmic region, leading to the release and activation of SigI6 (By similarity). Binds to and hydrolyzes insoluble and soluble xylan substrates. Has low enzymatic activity ; In the C-terminal section; belongs to the glycosyl hydrolase 10 (cellulase F) family.
 
  
 0.675
bglA
TIGRFAM: beta-galactosidase; KEGG: dtu:Dtur_1799 beta-galactosidase; PFAM: glycoside hydrolase family 1; Belongs to the glycosyl hydrolase 1 family.
    
 0.668
Cthe_1428
Beta-glucosidase; KEGG: hor:Hore_04820 beta-glucosidase; PFAM: glycoside hydrolase family 1; Belongs to the glycosyl hydrolase 1 family.
    
 0.668
celE
Glycoside hydrolase family 5; Multifunctional enzyme involved in the degradation of plant cell wall polysaccharides. Displays endoglucanase activity against carboxymethyl cellulose (CMC) and barley beta-glucan. Also catalyzes the deacetylation of acetylated birchwood xylan and glucomannan, with a preference for the latter, and of the synthetic substrate 4-nitrophenyl acetate (4-NPAc) ; In the C-terminal section; belongs to the carbohydrate esterase 2 (CE2) family.
 
 
0.658
Cthe_3141
PFAM: Carbohydrate binding family 6; Dockerin type 1; lipolytic protein G-D-S-L family; KEGG: bsu:BSU39120 putative esterase (lipoprotein).
 
 
0.625
celS
Glycoside hydrolase family 48; This enzyme catalyzes the exohydrolysis of 1,4-beta- glucosidic linkages in cellulose with a preference for amorphous or crystalline cellulose over carboxymethyl cellulose.
 
 
0.594
Cthe_0798
PFAM: lipolytic protein G-D-S-L family; Dockerin type 1; KEGG: ricin B lectin.
 
 
0.591
Your Current Organism:
Hungateiclostridium thermocellum
NCBI taxonomy Id: 203119
Other names: Clostridium thermocellum ATCC 27405, H. thermocellum ATCC 27405, Hungateiclostridium thermocellum ATCC 27405, Ruminiclostridium thermocellum ATCC 27405
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