STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Cthe_0701PFAM: Conserved carboxylase region; pyruvate carboxyltransferase; KEGG: cce:Ccel_1736 conserved carboxylase region. (465 aa)    
Predicted Functional Partners:
Cthe_0700
PFAM: biotin/lipoyl attachment domain-containing protein; KEGG: aoe:Clos_0442 biotin/lipoyl attachment domain-containing protein.
 
 0.998
Cthe_0509
Sodium ion-translocating decarboxylase, beta subunit; Tunnel subunit of the primary sodium pump glutaconyl-CoA decarboxylase (GCD).
 
 
 0.982
Cthe_1308
TIGRFAM: pyruvate, phosphate dikinase; KEGG: csc:Csac_1955 pyruvate phosphate dikinase; PFAM: PEP-utilizing protein; pyruvate phosphate dikinase PEP/pyruvate-binding; PEP-utilising protein mobile region; Belongs to the PEP-utilizing enzyme family.
  
 
 0.959
Cthe_3120
KEGG: cbl:CLK_0631 pyruvate ferredoxin oxidoreductase; TIGRFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Pyruvate/ketoisovalerate oxidoreductase, catalytic domain; Pyruvate-flavodoxin oxidoreductase, EKR domain; thiamine pyrophosphate TPP-binding domain-containing protein.
  
 
 0.959
pckG
Phosphoenolpyruvate carboxykinase (GTP); Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle; Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
   
 
 0.958
Cthe_0344
PFAM: malic protein NAD-binding; malic protein domain protein; KEGG: cce:Ccel_0138 malic protein NAD-binding.
  
 
 0.917
Cthe_0865
PFAM: thiamine pyrophosphate TPP-binding domain-containing protein; KEGG: cce:Ccel_0555 thiamine pyrophosphate protein domain protein TPP-binding.
   
 
 0.917
ldh-2
L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family.
    
 0.917
Cthe_1253
PFAM: pyruvate phosphate dikinase PEP/pyruvate-binding; KEGG: msi:Msm_0823 phosphoenolpyruvate synthase/pyruvate phosphate dikinase, PpsA.
  
 
 0.916
Cthe_2390
TIGRFAM: pyruvate/ketoisovalerate oxidoreductase, gamma subunit; KEGG: csc:Csac_1458 pyruvate/ketoisovalerate oxidoreductase, gamma subunit; PFAM: Pyruvate/ketoisovalerate oxidoreductase, catalytic domain.
   
 
 0.914
Your Current Organism:
Hungateiclostridium thermocellum
NCBI taxonomy Id: 203119
Other names: Clostridium thermocellum ATCC 27405, H. thermocellum ATCC 27405, Hungateiclostridium thermocellum ATCC 27405, Ruminiclostridium thermocellum ATCC 27405
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