STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
celEGlycoside hydrolase family 5; Multifunctional enzyme involved in the degradation of plant cell wall polysaccharides. Displays endoglucanase activity against carboxymethyl cellulose (CMC) and barley beta-glucan. Also catalyzes the deacetylation of acetylated birchwood xylan and glucomannan, with a preference for the latter, and of the synthetic substrate 4-nitrophenyl acetate (4-NPAc) ; In the C-terminal section; belongs to the carbohydrate esterase 2 (CE2) family. (814 aa)    
Predicted Functional Partners:
cipA
Cellulosome anchoring protein cohesin region; Acts as a scaffolding protein in the cellulosome. It promotes binding of cellulose to the catalytic domains of the cellulolytic enzymes.
  
 
 0.952
bglA
TIGRFAM: beta-galactosidase; KEGG: dtu:Dtur_1799 beta-galactosidase; PFAM: glycoside hydrolase family 1; Belongs to the glycosyl hydrolase 1 family.
  
 
 0.866
Cthe_0433
PFAM: glycoside hydrolase family 9; Dockerin type 1; KEGG: cce:Ccel_0753 glycoside hydrolase family 9.
  
 
0.826
rsgI3
PA14 domain protein; Anti-sigma factor for SigI3. Negatively regulates SigI3 activity through direct interaction. Binding of the polysaccharide substrate to the extracellular C-terminal sensing domain of RsgI3 may induce a conformational change in its N-terminal cytoplasmic region, leading to the release and activation of SigI3.
  
   0.825
Cthe_0274
PFAM: glycoside hydrolase family 9; Dockerin type 1; KEGG: cce:Ccel_0737 glycoside hydrolase family 9.
  
 
0.819
Cthe_2761
PFAM: glycoside hydrolase family 9; type 3a cellulose-binding domain protein; Dockerin type 1; KEGG: cce:Ccel_1249 glycoside hydrolase family 9; Belongs to the glycosyl hydrolase 9 (cellulase E) family.
  
 
0.818
Cthe_0275
PFAM: glycosyltransferase 36; carbohydrate binding; glycosyltransferase 36 associated; KEGG: cce:Ccel_2109 glycosyltransferase 36.
 
  
 0.810
celI
Glycoside hydrolase family 9; This enzyme catalyzes the endohydrolysis of 1,4-beta- glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans. Principally active against barley beta-glucan; Belongs to the glycosyl hydrolase 9 (cellulase E) family.
 
 
 0.803
Cthe_0291
KEGG: cac:CAC3546 hypothetical protein.
   
 
 0.803
Cthe_2951
KEGG: hypothetical protein.
   
 
 0.803
Your Current Organism:
Hungateiclostridium thermocellum
NCBI taxonomy Id: 203119
Other names: Clostridium thermocellum ATCC 27405, H. thermocellum ATCC 27405, Hungateiclostridium thermocellum ATCC 27405, Ruminiclostridium thermocellum ATCC 27405
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