STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Cthe_1569Cysteine synthase; KEGG: ckr:CKR_1913 hypothetical protein; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein. (438 aa)    
Predicted Functional Partners:
Cthe_1559
PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; KEGG: fsu:Fisuc_1079 cystathionine gamma-synthase.
 
 
0.958
metAA
Homoserine O-succinyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine; Belongs to the MetA family.
  
 
 0.956
Cthe_0645
PFAM: homocysteine S-methyltransferase; dihydropteroate synthase DHPS; Methionine synthase B12-binding module cap domain protein; cobalamin B12-binding domain protein; KEGG: sat:SYN_02703 5-methyltetrahydrofolate--homocysteine methyltransferase.
  
 
 0.955
Cthe_1560
PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: cpy:Cphy_1228 pyridoxal-5'-phosphate-dependent protein beta subunit.
 
 
 0.945
Cthe_2799
PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; KEGG: amt:Amet_3707 cystathionine gamma-synthase.
 
 
0.931
Cthe_1840
Cysteine synthase A; KEGG: dsy:DSY4189 hypothetical protein; TIGRFAM: cysteine synthase A; cysteine synthase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; Belongs to the cysteine synthase/cystathionine beta- synthase family.
 
 
 0.928
Cthe_2800
PFAM: aminotransferase class I and II; KEGG: kol:Kole_0146 aminotransferase class I and II.
   
 0.916
ahcY
Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
     
 0.911
Cthe_1842
TIGRFAM: O-acetylhomoserine/O-acetylserine sulfhydrylase; KEGG: dhd:Dhaf_1146 O-acetylhomoserine/O-acetylserine sulfhydrylase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein.
  
  
 
0.905
Cthe_0290
PFAM: homoserine dehydrogenase; amino acid-binding ACT domain protein; homoserine dehydrogenase NAD-binding; KEGG: amt:Amet_0566 homoserine dehydrogenase.
  
 
 0.851
Your Current Organism:
Hungateiclostridium thermocellum
NCBI taxonomy Id: 203119
Other names: Clostridium thermocellum ATCC 27405, H. thermocellum ATCC 27405, Hungateiclostridium thermocellum ATCC 27405, Ruminiclostridium thermocellum ATCC 27405
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