STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Cthe_1663PFAM: Endoribonuclease L-PSP; KEGG: chu:CHU_2496 endoribonuclease, inhibits protein synthesis. (142 aa)    
Predicted Functional Partners:
Cthe_1664
Transcriptional regulator, MerR family; KEGG: dsy:DSY1149 hypothetical protein; PFAM: regulatory protein MerR; SMART: regulatory protein MerR.
 
    0.752
Cthe_1665
PFAM: Hsp33 protein; KEGG: dsy:DSY1148 hypothetical protein.
 
  
 0.662
Cthe_1156
PFAM: DNA primase catalytic core domain; KEGG: mga:MGA_0013 hypothetical protein.
 
    0.643
Cthe_1135
PFAM: SEFIR domain protein; KEGG: bcq:BCQ_1344 hypothetical protein.
  
    0.567
rph
Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
  
 
 0.551
Cthe_3217
TIGRFAM: CRISPR-associated protein, TIGR02710 family; KEGG: tit:Thit_0694 CRISPR-associated protein, TIGR02710 family.
  
 
 0.493
Cthe_2325
Resolvase domain-containing protein; KEGG: sha:SH0056 staphylococcal casette chromosome site specific recombinase CcrC; PFAM: Resolvase domain; Recombinase; SMART: Resolvase domain.
  
     0.481
Cthe_0104
Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
  
   0.440
nnrD
Carbohydrate kinase, YjeF related protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow t [...]
  
  
 0.423
Cthe_1661
PFAM: transposase IS3/IS911 family protein; KEGG: cce:Ccel_1666 transposase IS3/IS911 family protein.
       0.420
Your Current Organism:
Hungateiclostridium thermocellum
NCBI taxonomy Id: 203119
Other names: Clostridium thermocellum ATCC 27405, H. thermocellum ATCC 27405, Hungateiclostridium thermocellum ATCC 27405, Ruminiclostridium thermocellum ATCC 27405
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