Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Cthe_1663PFAM: Endoribonuclease L-PSP; KEGG: chu:CHU_2496 endoribonuclease, inhibits protein synthesis. (142 aa)    
Predicted Functional Partners:
Cthe_1664
Transcriptional regulator, MerR family; KEGG: dsy:DSY1149 hypothetical protein; PFAM: regulatory protein MerR; SMART: regulatory protein MerR.
 
    0.753
Cthe_1665
PFAM: Hsp33 protein; KEGG: dsy:DSY1148 hypothetical protein.
 
  
 0.668
Cthe_1156
PFAM: DNA primase catalytic core domain; KEGG: mga:MGA_0013 hypothetical protein.
 
     0.640
Cthe_1135
PFAM: SEFIR domain protein; KEGG: bcq:BCQ_1344 hypothetical protein.
  
    0.567
Cthe_3217
TIGRFAM: CRISPR-associated protein, TIGR02710 family; KEGG: tit:Thit_0694 CRISPR-associated protein, TIGR02710 family.
  
   0.491
Cthe_2325
Resolvase domain-containing protein; KEGG: sha:SH0056 staphylococcal casette chromosome site specific recombinase CcrC; PFAM: Resolvase domain; Recombinase; SMART: Resolvase domain.
  
     0.481
tpiA
Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
  
 
 0.475
rph
Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
  
 
 0.466
Cthe_1661
PFAM: transposase IS3/IS911 family protein; KEGG: cce:Ccel_1666 transposase IS3/IS911 family protein.
       0.420
Cthe_0803
Pseudouridine synthase, RluA family; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family.
  
    0.410
Your Current Organism:
Hungateiclostridium thermocellum
NCBI taxonomy Id: 203119
Other names: Clostridium thermocellum ATCC 27405, H. thermocellum ATCC 27405, Hungateiclostridium thermocellum ATCC 27405, Ruminiclostridium thermocellum ATCC 27405
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