STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ureBTIGRFAM: urease, beta subunit; KEGG: hac:Hac_1532 urease subunit alpha; PFAM: Urease beta subunit; Belongs to the urease beta subunit family. (122 aa)    
Predicted Functional Partners:
ureC
KEGG: urease, alpha subunit; TIGRFAM: urease, alpha subunit; PFAM: amidohydrolase; Urease alpha-subunit domain-containing protein; Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
 0.999
ureA
TIGRFAM: urease, gamma subunit; KEGG: fjo:Fjoh_4837 urease subunit gamma; PFAM: Urease gamma subunit region; Belongs to the urease gamma subunit family.
 0.999
ureD
Urease accessory protein UreD; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
 
 
 0.983
ureE
UreE urease accessory domain-containing protein; Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly. Belongs to the UreE family.
 
  
 0.979
ureF
Urease accessory protein UreF; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
 
 
 0.973
ureG
Urease accessory protein UreG; Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
 
  
 0.939
Cthe_1819
TIGRFAM: urea ABC transporter, ATP-binding protein UrtE; PFAM: ABC transporter related; KEGG: pjd:Pjdr2_0561 UreA ABC transporter, ATP-binding protein UrtE; SMART: AAA ATPase.
  
  
 0.592
Cthe_3017
KEGG: cpy:Cphy_1737 hydrogenase accessory protein HypB; TIGRFAM: hydrogenase accessory protein HypB; PFAM: cobalamin synthesis protein P47K.
  
  
 0.580
Cthe_1822
KEGG: gym:GYMC10_1634 UreA ABC transporter, permease protein UrtB; TIGRFAM: urea ABC transporter, permease protein UrtB; PFAM: inner-membrane translocator; Belongs to the binding-protein-dependent transport system permease family.
  
  
 0.565
Cthe_1820
TIGRFAM: urea ABC transporter, ATP-binding protein UrtD; PFAM: ABC transporter related; KEGG: pjd:Pjdr2_0560 UreA ABC transporter, ATP-binding protein UrtD; SMART: AAA ATPase.
  
  
 0.563
Your Current Organism:
Hungateiclostridium thermocellum
NCBI taxonomy Id: 203119
Other names: Clostridium thermocellum ATCC 27405, H. thermocellum ATCC 27405, Hungateiclostridium thermocellum ATCC 27405, Ruminiclostridium thermocellum ATCC 27405
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