STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Cthe_2100KEGG: cce:Ccel_0164 transcriptional regulator, AbrB family; TIGRFAM: transcriptional regulator, AbrB family; PFAM: SpoVT/AbrB domain-containing protein. (79 aa)    
Predicted Functional Partners:
Cthe_0812
Sporulation transcriptional activator Spo0A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.
  
   
 0.844
Cthe_3087
Sporulation transcriptional activator Spo0A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.
  
   
 0.655
Cthe_1021
Stage IV sporulation protein A; ATPase. Has a role at an early stage in the morphogenesis of the spore coat.
  
     0.640
Cthe_2618
TIGRFAM: sporulation transcriptional regulator SpoIIID; KEGG: cpy:Cphy_0210 sporulation transcriptional regulator SpoIIID.
  
   
 0.610
Cthe_0843
TIGRFAM: stage III sporulation protein AC; KEGG: cce:Ccel_1914 stage III sporulation protein AC.
  
   
 0.603
Cthe_2375
KEGG: cce:Ccel_0005 hypothetical protein.
  
   
 0.579
spoIIAB
Putative anti-sigma regulatory factor, serine/threonine protein kinase; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.
  
  
 0.573
Cthe_0122
KEGG: cce:Ccel_2282 stage V sporulation protein AC; TIGRFAM: stage V sporulation protein AC; PFAM: SpoVA protein.
  
     0.547
Cthe_0305
KEGG: cce:Ccel_1398 DNA gyrase subunit B domain protein; PFAM: DNA gyrase subunit B domain protein; TOPRIM domain-containing protein; DNA topoisomerase type IIA subunit B region 2 domain protein; ATP-binding region ATPase domain protein; SMART: DNA topoisomerase II.
      
 0.544
Cthe_1836
KEGG: dae:Dtox_1722 hypothetical protein.
   
  
 0.533
Your Current Organism:
Hungateiclostridium thermocellum
NCBI taxonomy Id: 203119
Other names: Clostridium thermocellum ATCC 27405, H. thermocellum ATCC 27405, Hungateiclostridium thermocellum ATCC 27405, Ruminiclostridium thermocellum ATCC 27405
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