STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Cthe_2208Transcriptional repressor, LexA family; PFAM: LexA DNA-binding domain protein; KEGG: cac:CAC1832 LexA repressor. (195 aa)    
Predicted Functional Partners:
recA
recA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
  
 
 0.964
dinB
DNA-directed DNA polymerase; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.
 
 
 0.859
Cthe_0814
DNA repair protein RecN; May be involved in recombinational repair of damaged DNA.
   
  
 0.544
Cthe_2202
KEGG: eat:EAT1b_1173 hypothetical protein.
  
    0.471
Cthe_2212
KEGG: cce:Ccel_0125 transcriptional regulator, AraC family; PFAM: helix-turn-helix- domain containing protein AraC type; Cupin 2 conserved barrel domain protein; SMART: Helix-turn-helix, AraC domain.
  
   0.459
Cthe_0582
Multi-sensor signal transduction histidine kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; PAS fold domain protein; histidine kinase A domain protein; KEGG: dal:Dalk_2282 PAS/PAC sensor signal transduction histidine kinase; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein; PAC repeat-containing protein; GAF domain protein.
 
  
 0.446
Cthe_2515
PFAM: CMP/dCMP deaminase zinc-binding; KEGG: cyc:PCC7424_5071 CMP/dCMP deaminase zinc-binding.
   
  
 0.445
Cthe_1649
PFAM: phage antirepressor protein; BRO domain protein; KEGG: sga:GALLO_0430 putative prophage antirepressor.
  
  
 0.430
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
  
  
 0.410
cinA
KEGG: cce:Ccel_0674 competence/damage-inducible protein CinA; TIGRFAM: competence/damage-inducible protein CinA; molybdenum cofactor synthesis domain protein; PFAM: CinA domain protein; molybdopterin binding domain.
     
 0.410
Your Current Organism:
Hungateiclostridium thermocellum
NCBI taxonomy Id: 203119
Other names: Clostridium thermocellum ATCC 27405, H. thermocellum ATCC 27405, Hungateiclostridium thermocellum ATCC 27405, Ruminiclostridium thermocellum ATCC 27405
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