STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Cthe_3015KEGG: cpy:Cphy_1739 hydrogenase assembly chaperone HypC/HupF; TIGRFAM: hydrogenase assembly chaperone hypC/hupF; PFAM: hydrogenase expression/formation protein (HUPF/HYPC). (75 aa)    
Predicted Functional Partners:
Cthe_3014
KEGG: cpy:Cphy_1740 hydrogenase formation HypD protein; TIGRFAM: hydrogenase expression/formation protein HypD; PFAM: hydrogenase formation HypD protein.
 
 
 0.998
Cthe_3013
KEGG: cpy:Cphy_1741 hydrogenase expression/formation protein HypE; TIGRFAM: hydrogenase expression/formation protein HypE; PFAM: AIR synthase related protein domain protein; AIR synthase related protein.
 
 
 0.996
Cthe_3016
KEGG: cpy:Cphy_1738 (NiFe) hydrogenase maturation protein HypF; TIGRFAM: [NiFe] hydrogenase maturation protein HypF; PFAM: SUA5/yciO/yrdC domain; acylphosphatase.
 
 
 0.983
Cthe_3017
KEGG: cpy:Cphy_1737 hydrogenase accessory protein HypB; TIGRFAM: hydrogenase accessory protein HypB; PFAM: cobalamin synthesis protein P47K.
 
  
 0.977
hypA
Hydrogenase expression/synthesis HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
 
  
 0.956
Cthe_3019
KEGG: cpy:Cphy_1735 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein.
 
  
 0.934
Cthe_1060
PFAM: AIR synthase related protein domain protein; AIR synthase related protein; KEGG: cce:Ccel_1681 AIR synthase related protein domain protein.
  
 
 0.918
Cthe_3024
PFAM: NADH/Ubiquinone/plastoquinone (complex I); NADH-Ubiquinone oxidoreductase (complex I) chain 5/L domain protein; KEGG: cpy:Cphy_1730 NADH dehydrogenase (quinone).
 
  
 0.804
Cthe_3021
PFAM: NADH dehydrogenase (ubiquinone) 30 kDa subunit; KEGG: cpy:Cphy_1733 ech hydrogenase, subunit EchD, putative.
  
  
 0.795
Cthe_3020
PFAM: NADH-ubiquinone oxidoreductase chain 49kDa; nickel-dependent hydrogenase large subunit; KEGG: cpy:Cphy_1734 NADH-ubiquinone oxidoreductase chain 49kDa; Belongs to the complex I 49 kDa subunit family.
  
 
 0.689
Your Current Organism:
Hungateiclostridium thermocellum
NCBI taxonomy Id: 203119
Other names: Clostridium thermocellum ATCC 27405, H. thermocellum ATCC 27405, Hungateiclostridium thermocellum ATCC 27405, Ruminiclostridium thermocellum ATCC 27405
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.