STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Cthe_3039PFAM: cell divisionFtsK/SpoIIIE; DNA translocase ftsK gamma; KEGG: cce:Ccel_0601 cell divisionFtsK/SpoIIIE; Belongs to the FtsK/SpoIIIE/SftA family. (830 aa)    
Predicted Functional Partners:
Cthe_2378
TIGRFAM: parB-like partition protein; PFAM: ParB domain protein nuclease; KEGG: cce:Ccel_0008 ParB-like partition protein; SMART: ParB domain protein nuclease; Belongs to the ParB family.
  
  
 0.680
Cthe_1373
PFAM: YD repeat-containing protein; KEGG: cbe:Cbei_4376 YD repeat-containing protein.
  
 
 0.643
Cthe_0637
KEGG: bsu:BSU31910 hypothetical protein; Belongs to the WXG100 family.
  
 
 0.627
Cthe_0442
Polypeptide-transport-associated domain protein FtsQ-type; Essential cell division protein.
   
 
 0.611
Cthe_2362
TIGRFAM: parB-like partition protein; PFAM: ParB domain protein nuclease; KEGG: cce:Ccel_3483 ParB-like partition protein; SMART: ParB domain protein nuclease; Belongs to the ParB family.
  
  
 0.602
Cthe_3040
PFAM: Protein of unknown function DUF2383; KEGG: aoe:Clos_1705 hypothetical protein.
  
  
 0.589
Cthe_1966
Hypothetical protein; KEGG: esi:Exig_2157 succinate dehydrogenase flavoprotein subunit.
  
 
 0.552
Cthe_1127
PFAM: integrase family protein; integrase domain protein SAM domain protein; KEGG: cpo:COPRO5265_0041 tyrosine recombinase XerD; Belongs to the 'phage' integrase family.
  
   
 0.531
ispH
Hydroxymethylbutenyl pyrophosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family.
 
  
 0.500
dnaA
Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.
  
  
 0.487
Your Current Organism:
Hungateiclostridium thermocellum
NCBI taxonomy Id: 203119
Other names: Clostridium thermocellum ATCC 27405, H. thermocellum ATCC 27405, Hungateiclostridium thermocellum ATCC 27405, Ruminiclostridium thermocellum ATCC 27405
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