STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Sde_2692Putative bifunctional family GT51 b-glycosyltransferase/PBP transpeptidase; Candidate murein polymerase. (846 aa)    
Predicted Functional Partners:
Sde_0825
Putative bifunctional family GT51 b-glycosyltransferase/PBP transpeptidase; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits).
 
 
0.950
Sde_0603
Putative bifunctional family GT51 b-glycosyltransferase/PBP transpeptidase; Candidate murein polymerase.
  
  
0.926
Sde_3337
Penicillin-binding protein 6. Serine peptidase. MEROPS family S11; Belongs to the peptidase S11 family.
     
 0.921
Sde_3145
LppC putative lipoprotein.
    
 
 0.763
mrdA
PAS/PAC sensor signal transduction histidine kinase / peptidoglycan glycosyltransferase; Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily.
 
 
 
 0.736
murC
UDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family.
  
   
 0.667
murA
UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily.
  
   
 0.651
ftsI
Peptidoglycan synthetase FtsI; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum.
 
 
 
 0.632
Sde_2024
Putative lytic murein transglycosylase.
 
  
 0.623
mrdB
Rod shape-determining protein RodA; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily.
  
   
 0.609
Your Current Organism:
Saccharophagus degradans
NCBI taxonomy Id: 203122
Other names: Microbulbifer degradans 2-40, Microbulbifer sp. 2-40, S. degradans 2-40, Saccharophagus degradans 2-40, Saccharophagus degradans ATCC 43961, Saccharophagus degradans str. 2-40, Saccharophagus degradans strain 2-40, bacterium 2-40
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