node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Sde_0386 | Sde_3174 | Sde_0386 | Sde_3174 | Putative CMP-KDO KDO transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | KpsF/GutQ family protein. | 0.898 |
Sde_0386 | Sde_3175 | Sde_0386 | Sde_3175 | Putative CMP-KDO KDO transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | Phosphatase kdsC; Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8- phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate; Belongs to the KdsC family. | 0.597 |
Sde_0386 | Sde_3178 | Sde_0386 | Sde_3178 | Putative CMP-KDO KDO transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | PAS/PAC sensor signal transduction histidine kinase. | 0.546 |
Sde_0386 | kdsA | Sde_0386 | Sde_1244 | Putative CMP-KDO KDO transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | 2-dehydro-3-deoxyphosphooctonate aldolase; Belongs to the KdsA family. | 0.848 |
Sde_0386 | kdsB | Sde_0386 | Sde_2058 | Putative CMP-KDO KDO transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | 3-deoxy-D-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. | 0.985 |
Sde_0386 | lpx11A | Sde_0386 | Sde_0854 | Putative CMP-KDO KDO transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. | 0.852 |
Sde_0386 | lpxK | Sde_0386 | Sde_2059 | Putative CMP-KDO KDO transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | lipid-A-disaccharide synthase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). | 0.998 |
Sde_3173 | Sde_3174 | Sde_3173 | Sde_3174 | K+-dependent Na+/Ca+ exchanger related-protein. | KpsF/GutQ family protein. | 0.968 |
Sde_3173 | Sde_3175 | Sde_3173 | Sde_3175 | K+-dependent Na+/Ca+ exchanger related-protein. | Phosphatase kdsC; Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8- phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate; Belongs to the KdsC family. | 0.899 |
Sde_3173 | Sde_3178 | Sde_3173 | Sde_3178 | K+-dependent Na+/Ca+ exchanger related-protein. | PAS/PAC sensor signal transduction histidine kinase. | 0.624 |
Sde_3173 | lptA | Sde_3173 | Sde_3177 | K+-dependent Na+/Ca+ exchanger related-protein. | OstA-like protein; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm. | 0.623 |
Sde_3173 | lptC | Sde_3173 | Sde_3176 | K+-dependent Na+/Ca+ exchanger related-protein. | Protein of unknown function DUF1239; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA. | 0.577 |
Sde_3174 | Sde_0386 | Sde_3174 | Sde_0386 | KpsF/GutQ family protein. | Putative CMP-KDO KDO transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | 0.898 |
Sde_3174 | Sde_3173 | Sde_3174 | Sde_3173 | KpsF/GutQ family protein. | K+-dependent Na+/Ca+ exchanger related-protein. | 0.968 |
Sde_3174 | Sde_3175 | Sde_3174 | Sde_3175 | KpsF/GutQ family protein. | Phosphatase kdsC; Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8- phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate; Belongs to the KdsC family. | 0.997 |
Sde_3174 | Sde_3178 | Sde_3174 | Sde_3178 | KpsF/GutQ family protein. | PAS/PAC sensor signal transduction histidine kinase. | 0.874 |
Sde_3174 | kdsA | Sde_3174 | Sde_1244 | KpsF/GutQ family protein. | 2-dehydro-3-deoxyphosphooctonate aldolase; Belongs to the KdsA family. | 0.990 |
Sde_3174 | kdsB | Sde_3174 | Sde_2058 | KpsF/GutQ family protein. | 3-deoxy-D-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. | 0.901 |
Sde_3174 | lptA | Sde_3174 | Sde_3177 | KpsF/GutQ family protein. | OstA-like protein; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm. | 0.636 |
Sde_3174 | lptC | Sde_3174 | Sde_3176 | KpsF/GutQ family protein. | Protein of unknown function DUF1239; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA. | 0.763 |