node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Sde_0830 | Sde_3185 | Sde_0830 | Sde_3185 | Catalase. | Protein-methionine-S-oxide reductase. | 0.415 |
Sde_0888 | Sde_3185 | Sde_0888 | Sde_3185 | Fumarase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | Protein-methionine-S-oxide reductase. | 0.460 |
Sde_1736 | Sde_3185 | Sde_1736 | Sde_3185 | Protein of unknown function DUF1315. | Protein-methionine-S-oxide reductase. | 0.774 |
Sde_2010 | Sde_3185 | Sde_2010 | Sde_3185 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Protein-methionine-S-oxide reductase. | 0.402 |
Sde_2010 | msrA | Sde_2010 | Sde_1862 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Peptide methionine sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. | 0.538 |
Sde_3185 | Sde_0830 | Sde_3185 | Sde_0830 | Protein-methionine-S-oxide reductase. | Catalase. | 0.415 |
Sde_3185 | Sde_0888 | Sde_3185 | Sde_0888 | Protein-methionine-S-oxide reductase. | Fumarase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | 0.460 |
Sde_3185 | Sde_1736 | Sde_3185 | Sde_1736 | Protein-methionine-S-oxide reductase. | Protein of unknown function DUF1315. | 0.774 |
Sde_3185 | Sde_2010 | Sde_3185 | Sde_2010 | Protein-methionine-S-oxide reductase. | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.402 |
Sde_3185 | Sde_3186 | Sde_3185 | Sde_3186 | Protein-methionine-S-oxide reductase. | Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase. | 0.765 |
Sde_3185 | Sde_3187 | Sde_3185 | Sde_3187 | Protein-methionine-S-oxide reductase. | Conserved hypothetical protein. | 0.494 |
Sde_3185 | grpE | Sde_3185 | Sde_2734 | Protein-methionine-S-oxide reductase. | GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...] | 0.414 |
Sde_3185 | msrA | Sde_3185 | Sde_1862 | Protein-methionine-S-oxide reductase. | Peptide methionine sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. | 0.989 |
Sde_3186 | Sde_3185 | Sde_3186 | Sde_3185 | Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase. | Protein-methionine-S-oxide reductase. | 0.765 |
Sde_3186 | Sde_3187 | Sde_3186 | Sde_3187 | Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase. | Conserved hypothetical protein. | 0.543 |
Sde_3187 | Sde_3185 | Sde_3187 | Sde_3185 | Conserved hypothetical protein. | Protein-methionine-S-oxide reductase. | 0.494 |
Sde_3187 | Sde_3186 | Sde_3187 | Sde_3186 | Conserved hypothetical protein. | Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase. | 0.543 |
grpE | Sde_3185 | Sde_2734 | Sde_3185 | GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...] | Protein-methionine-S-oxide reductase. | 0.414 |
msrA | Sde_2010 | Sde_1862 | Sde_2010 | Peptide methionine sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.538 |
msrA | Sde_3185 | Sde_1862 | Sde_3185 | Peptide methionine sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. | Protein-methionine-S-oxide reductase. | 0.989 |