STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
OEOE_0289Heat shock protein Hsp20; Belongs to the small heat shock protein (HSP20) family. (148 aa)    
Predicted Functional Partners:
dnaK
Molecular chaperone; Acts as a chaperone; Belongs to the heat shock protein 70 family.
  
 
 0.732
OEOE_0514
ATP-binding subunit of Clp protease and DnaK/DnaJ chaperones; Belongs to the ClpA/ClpB family.
  
 
 0.684
OEOE_0572
ATP-binding subunit of Clp protease and DnaK/DnaJ chaperones; Belongs to the ClpA/ClpB family.
  
 
 0.684
OEOE_0640
ATP-binding subunit of Clp protease and DnaK/DnaJ chaperones; Belongs to the ClpA/ClpB family.
  
 
 0.684
grpE
Molecular chaperone GrpE (heat shock protein); Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. [...]
  
  
 0.682
OEOE_1308
DnaJ-class molecular chaperone with C-terminal Zn finger domain.
  
 
 0.644
OEOE_0290
Permease of the major facilitator superfamily.
       0.497
OEOE_0789
Serine/threonine protein kinase with beta-lactam (PASTA) domains.
  
 
 0.492
groS
Co-chaperonin GroES (HSP10); Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter.
  
  
 0.450
hslO
Disulfide bond chaperones of the HSP33 family; Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.
   
  
 0.447
Your Current Organism:
Oenococcus oeni
NCBI taxonomy Id: 203123
Other names: O. oeni PSU-1, Oenococcus oeni PSU-1, Oenococcus oeni str. PSU-1, Oenococcus oeni strain PSU-1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.