STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
OEOE_1012tRNA nucleotidyltransferase/poly(A) polymerase. (399 aa)    
Predicted Functional Partners:
birA
Biotin operon repressor; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.
 
  
 0.885
OEOE_1011
TPR repeat containing protein.
 
     0.826
rnhB
RNase HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
     
 0.805
OEOE_1017
Hypothetical protein; Belongs to the UPF0346 family.
 
     0.803
OEOE_1013
Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.
       0.800
OEOE_1014
Hypothetical protein.
       0.781
OEOE_1018
Predicted GTPase; Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity; Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.
  
    0.775
OEOE_1016
Hypothetical protein.
       0.768
OEOE_1015
Lysophospholipase L1-like esterase.
       0.763
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
 
   
 0.696
Your Current Organism:
Oenococcus oeni
NCBI taxonomy Id: 203123
Other names: O. oeni PSU-1, Oenococcus oeni PSU-1, Oenococcus oeni str. PSU-1, Oenococcus oeni strain PSU-1
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