STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tery_0400PFAM: adenylyl cyclase class-3/4/guanylyl cyclase GAF Tetratricopeptide TPR_3; SMART: PAS; KEGG: ava:Ava_0091 adenylate/guanylate cyclase. (864 aa)    
Predicted Functional Partners:
ndk
Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
    
 0.901
Tery_2926
PFAM: pyruvate kinase PEP-utilising enzyme, mobile region; KEGG: ava:Ava_1694 pyruvate kinase; Belongs to the pyruvate kinase family.
    
 0.901
Tery_2653
(p)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.
     
  0.900
ribBA
GTP cyclohydrolase II / 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
    
  0.811
Tery_4447
Multi-sensor hybrid histidine kinase; KEGG: ana:all2875 two-component hybrid sensor and regulator; TIGRFAM: PAS sensor protein; PFAM: CBS domain containing protein response regulator receiveR GAF ATP-binding region, ATPase-like histidine kinase A-like PAS fold-3 PAS fold; SMART: PAS PAC motif.
  
 
 0.806
moaA
GTP cyclohydrolase subunit MoaA; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate.
   
  0.803
folE
PFAM: GTP cyclohydrolase I; KEGG: ana:alr5287 GTP cyclohydrolase I.
     
  0.800
folE-2
PFAM: GTP cyclohydrolase I; KEGG: ava:Ava_1949 GTP cyclohydrolase I.
     
  0.800
Tery_3155
PFAM: adenylyl cyclase class-3/4/guanylyl cyclase response regulator receiveR GAF ATP-binding region, ATPase-like histidine kinase A-like; KEGG: ana:all4963 adenylate cyclase carring two-component hybrid sensor and regulator domains.
 
 
0.720
Tery_2905
PFAM: cyclic nucleotide-binding; KEGG: ava:Ava_3692 cyclic nucleotide-binding domain (cNMP-BD) protein.
 
 
 0.694
Your Current Organism:
Trichodesmium erythraeum
NCBI taxonomy Id: 203124
Other names: T. erythraeum IMS101, Trichodesmium erythraeum IMS101, Trichodesmium erythraeum str. IMS101, Trichodesmium erythraeum strain IMS101, Trichodesmium sp. IMS101
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