STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cofHFO synthase subunit 2; Catalyzes the radical-mediated synthesis of 5-amino-5-(4- hydroxybenzyl)-6-(D-ribitylimino)-5,6-dihydrouracil from 5-amino-6-(D- ribitylamino)uracil and L-tyrosine. (398 aa)    
Predicted Functional Partners:
cofG
FO synthase subunit 1; Catalyzes the radical-mediated synthesis of 7,8-didemethyl-8- hydroxy-5-deazariboflavin from 5-amino-5-(4-hydroxybenzyl)-6-(D- ribitylimino)-5,6-dihydrouracil.
 
  
 0.998
Tery_4980
Response regulator receiver modulated diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); KEGG: ana:all0219 hypothetical protein; TIGRFAM: PAS sensor protein diguanylate cyclase; PFAM: conserved hypothetical protein EAL response regulator receiveR PAS fold-3 PAS fold; SMART: PAS.
 
 
 0.852
thiG
Thiazole biosynthesis; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
  
 
 0.824
thiC
Thiamine biosynthesis protein ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family.
  
  
 0.774
thiE
Thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.
  
  
 0.765
Tery_0665
Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); KEGG: ana:alr3170 hypothetical protein; TIGRFAM: PAS sensor protein diguanylate cyclase; PFAM: conserved hypothetical protein EAL PAS fold-3 PAS fold-4 PAS fold; SMART: PAS PAC motif.
 
 
 0.732
Tery_2584
TIGRFAM: thiamine biosynthesis protein ThiS; PFAM: thiamineS; KEGG: ava:Ava_5046 hypothetical protein.
  
  
 0.682
Tery_2499
TIGRFAM: diguanylate cyclase; PFAM: conserved hypothetical protein EAL; KEGG: ana:all4897 hypothetical protein.
 
  
 0.679
Tery_4817
PFAM: response regulator receiveR GAF Stage II sporulation E; SMART: Protein phosphatase 2C-like; KEGG: ana:all1703 two-component response regulator.
  
  
 0.634
Tery_1508
KEGG: ava:Ava_0550 3-octaprenyl-4-hydroxybenzoate carboxy-lyase.
 
   
 0.621
Your Current Organism:
Trichodesmium erythraeum
NCBI taxonomy Id: 203124
Other names: T. erythraeum IMS101, Trichodesmium erythraeum IMS101, Trichodesmium erythraeum str. IMS101, Trichodesmium erythraeum strain IMS101, Trichodesmium sp. IMS101
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