Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Tery_4232TIGRFAM: ATP-dependent DNA helicase PcrA; PFAM: UvrD/REP helicase; KEGG: ana:all4495 DNA helicase II. (781 aa)    
Predicted Functional Partners:
Tery_2533
PFAM: UvrD/REP helicase; KEGG: ava:Ava_1425 UvrD/REP helicase.
  
  
 
0.988
Tery_4233
PFAM: UvrD/REP helicase; KEGG: tcx:Tcr_0212 UvrD/REP helicase.
     
  0.900
Tery_0165
PFAM: DNA recombination protein, RuvA; KEGG: ava:Ava_2820 Holliday junction DNA helicase motor protein.
  
 
 0.886
Tery_0168
Holliday junction DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.
  
 
 0.886
Tery_1462
KEGG: cya:CYA_1550 replicative DNA helicase; TIGRFAM: Protein splicing (intein) site; PFAM: DnaB-like helicase-like; SMART: Hedgehog/intein hint domain-like Hedgehog/intein hint-like.
  
 0.868
uvrC
Excinuclease ABC subunit C; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
  
  
 0.855
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
 
 0.830
Tery_1571
TIGRFAM: ATP-dependent DNA helicase, RecQ family; PFAM: helicase-like type III restriction enzyme, res subunit DEAD/DEAH box helicase-like; KEGG: ana:alr3451 ATP-dependent DNA helicase.
  
 0.803
dnaG
DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.
 
 
 0.770
Tery_0504
TIGRFAM: DNA mismatch repair protein MutL; PFAM: ATP-binding region, ATPase-like DNA mismatch repair protein-like; KEGG: ana:alr3055 DNA mismatch repair protein; Belongs to the DNA mismatch repair MutL/HexB family.
   
 0.764
Your Current Organism:
Trichodesmium erythraeum
NCBI taxonomy Id: 203124
Other names: T. erythraeum IMS101, Trichodesmium erythraeum IMS101, Trichodesmium erythraeum str. IMS101, Trichodesmium erythraeum strain IMS101, Trichodesmium sp. IMS101
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.