Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
birABiotin acetyl-CoA carboxylase ligase. (248 aa)    
Predicted Functional Partners:
pccB
propionyl-CoA carboxylase beta chain.
  
 
 0.944
bccA
Biotin carboxylase.
 
  
 0.938
pca
Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.
  
 
 0.815
folPXK
7,8-dihydroneopterin aldolase/epimerase/oxygenase; DHPS/FolB/HPPK; implicated resistence to sulfonamide.
  
  
 0.716
ribG
Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
  
  
 0.543
nadE
NH(3)-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
  
  
 0.499
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
     
 0.451
tadA
Unknown; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family.
  
    0.443
TWT_592
Ribosomal protein acetyltransferase.
   
    0.427
TWT_593
Holo-[acyl-carrier protein] synthase; Belongs to the P-Pant transferase superfamily.
  
  
 0.423
Your Current Organism:
Tropheryma whipplei
NCBI taxonomy Id: 203267
Other names: T. whipplei str. Twist, Tropheryma whipplei Twist, Tropheryma whipplei str. Twist, Tropheryma whipplei strain Twist
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