Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
rmlBdTDP-glucose 4,6-dehydratase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily. (327 aa)    
Predicted Functional Partners:
rmlA
Glucose-1-phosphate thymidylyltransferase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family.
 
 
 0.999
rmlC
dTDP-4-dehydrorhamnose 3,5-epimerase.
 
 
 0.998
rmlD
dTDP-4-dehydrorhamnose reductase; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.
 
 
0.993
rpoB
DNA-directed RNA polymerase beta chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
 
      0.529
rfe
Undecaprenyl-phosphate alpha-N-acetylglucosaminyltransferase.
  
  
 0.489
wbbL
Glycosyl transferase.
  
  
 0.470
hemL
Glutamate-1-semialdehyde 2,1-aminomutase.
     
 0.429
TWT_257
Unknown.
  
    0.413
TWT_028
Unknown.
       0.405
Your Current Organism:
Tropheryma whipplei
NCBI taxonomy Id: 203267
Other names: T. whipplei str. Twist, Tropheryma whipplei Twist, Tropheryma whipplei str. Twist, Tropheryma whipplei strain Twist
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