Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
msrBmethionine-R-sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. (341 aa)    
Predicted Functional Partners:
BFO_1319
Putative lipoprotein.
   
 0.977
BFO_1720
Antioxidant, AhpC/TSA family; Identified by match to protein family HMM PF00085; match to protein family HMM PF00578; match to protein family HMM PF08534.
   
 0.977
BFO_3147
Hypothetical protein.
   
 0.977
BFO_1379
Cytochrome C biogenesis protein transmembrane region; Identified by match to protein family HMM PF02683.
   
 
 0.969
BFO_2629
Glutaredoxin; Identified by match to protein family HMM PF00462.
  
 
 0.859
BFO_1755
Pyridine nucleotide-disulfide oxidoreductase; Identified by match to protein family HMM PF00070; match to protein family HMM PF00581; match to protein family HMM PF01206; match to protein family HMM PF02852; match to protein family HMM PF07992; Belongs to the sulfur carrier protein TusA family.
  
 
 0.815
BFO_1338
Glutathione peroxidase; Identified by match to protein family HMM PF00255; Belongs to the glutathione peroxidase family.
  
 
 0.738
grpE
Co-chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-depend [...]
   
 
 0.710
metH
Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
  
  
 0.690
trxB
Thioredoxin-disulfide reductase; Identified by match to protein family HMM PF00070; match to protein family HMM PF07992; match to protein family HMM TIGR01292.
  
  
 0.690
Your Current Organism:
Tannerella forsythia
NCBI taxonomy Id: 203275
Other names: T. forsythia 92A2, Tannerella forsythia 92A2
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