STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KIQ11973.1Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. (292 aa)    
Predicted Functional Partners:
KIQ10053.1
Dihydrofolate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.985
FolB
Diguanylate cyclase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin.
  
 0.983
folE
GTP cyclohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.977
KIQ11890.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.861
KIQ11889.1
Phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.701
KIQ09954.1
Branched-chain amino acid aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.602
KIQ05792.1
Para-aminobenzoate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.567
KIQ09283.1
DeoR faimly transcriptional regulator; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
     
 0.530
guaB
Inosine-5-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
  
  
 0.517
KIQ04983.1
Hemolysin; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
    0.493
Your Current Organism:
Curtobacterium flaccumfaciens
NCBI taxonomy Id: 2035
Other names: Bacterium flaccumfaciens, Bacterium poinsettiae, C. flaccumfaciens, CIP 107085, Corynebacterium betae, Corynebacterium flaccumfaciens, Corynebacterium flaccumfaciens subsp. betae, Corynebacterium flaccumfaciens subsp. flaccumfaciens, Corynebacterium flaccumfaciens subsp. oortii, Corynebacterium flaccumfaciens subsp. poinsettiae, Corynebacterium oortii, Curtibacterium flaccumfaciens, ICMP 2584, JCM 9670, LMG 3645, LMG:3645, Phytomonas flaccumfaciens, Phytomonas poinsettiae, Pseudomonas flaccumfaciens
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.