node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
argI | speB | Bfl032 | Bfl253 | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. | Agmatine ureohydrolase; Catalyzes the formation of putrescine from agmatine. | 0.762 |
argI | thrA | Bfl032 | Bfl111 | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. | Aspartokinase I/homoserine dehydrogenase I; COG category=E; In the C-terminal section; belongs to the homoserine dehydrogenase family. | 0.529 |
efp | speB | Bfl072 | Bfl253 | Elongation factor P (EF-P); Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome. Modification of Lys-33 is required for alleviation; Belongs to the elongation factor P family. | Agmatine ureohydrolase; Catalyzes the formation of putrescine from agmatine. | 0.423 |
efp | thrA | Bfl072 | Bfl111 | Elongation factor P (EF-P); Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome. Modification of Lys-33 is required for alleviation; Belongs to the elongation factor P family. | Aspartokinase I/homoserine dehydrogenase I; COG category=E; In the C-terminal section; belongs to the homoserine dehydrogenase family. | 0.733 |
efp | tyrA | Bfl072 | Bfl178 | Elongation factor P (EF-P); Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome. Modification of Lys-33 is required for alleviation; Belongs to the elongation factor P family. | Chorismate mutase/prephenate dehydrogenase; COG category=E. | 0.467 |
fumC | lysA | Bfl373 | Bfl263 | Fumarate hydratase class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. | 0.518 |
fumC | speB | Bfl373 | Bfl253 | Fumarate hydratase class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. | Agmatine ureohydrolase; Catalyzes the formation of putrescine from agmatine. | 0.539 |
fumC | thrA | Bfl373 | Bfl111 | Fumarate hydratase class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. | Aspartokinase I/homoserine dehydrogenase I; COG category=E; In the C-terminal section; belongs to the homoserine dehydrogenase family. | 0.402 |
glnA | leuS | Bfl618 | Bfl313 | Glutamine synthetase; COG category=E. | leucyl-tRNA synthetase; COG category=J; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.450 |
glnA | speB | Bfl618 | Bfl253 | Glutamine synthetase; COG category=E. | Agmatine ureohydrolase; Catalyzes the formation of putrescine from agmatine. | 0.568 |
glnA | thrA | Bfl618 | Bfl111 | Glutamine synthetase; COG category=E. | Aspartokinase I/homoserine dehydrogenase I; COG category=E; In the C-terminal section; belongs to the homoserine dehydrogenase family. | 0.447 |
glnA | tyrA | Bfl618 | Bfl178 | Glutamine synthetase; COG category=E. | Chorismate mutase/prephenate dehydrogenase; COG category=E. | 0.428 |
glnA | ureG | Bfl618 | Bfl521 | Glutamine synthetase; COG category=E. | Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase; Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG. | 0.446 |
leuS | glnA | Bfl313 | Bfl618 | leucyl-tRNA synthetase; COG category=J; Belongs to the class-I aminoacyl-tRNA synthetase family. | Glutamine synthetase; COG category=E. | 0.450 |
leuS | speB | Bfl313 | Bfl253 | leucyl-tRNA synthetase; COG category=J; Belongs to the class-I aminoacyl-tRNA synthetase family. | Agmatine ureohydrolase; Catalyzes the formation of putrescine from agmatine. | 0.461 |
lysA | fumC | Bfl263 | Bfl373 | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. | Fumarate hydratase class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. | 0.518 |
lysA | speB | Bfl263 | Bfl253 | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. | Agmatine ureohydrolase; Catalyzes the formation of putrescine from agmatine. | 0.494 |
lysA | thrA | Bfl263 | Bfl111 | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. | Aspartokinase I/homoserine dehydrogenase I; COG category=E; In the C-terminal section; belongs to the homoserine dehydrogenase family. | 0.984 |
metK | speB | Bfl252 | Bfl253 | S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | Agmatine ureohydrolase; Catalyzes the formation of putrescine from agmatine. | 0.537 |
metK | thrA | Bfl252 | Bfl111 | S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | Aspartokinase I/homoserine dehydrogenase I; COG category=E; In the C-terminal section; belongs to the homoserine dehydrogenase family. | 0.730 |