node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ftsL | hemD | Bfl135 | Bfl581 | Cell division protein FtsL; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. | Uroporphyrinogen III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | 0.573 |
ftsL | ilvM | Bfl135 | Bfl592 | Cell division protein FtsL; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. | Acetolactate synthase II, small subunit; COG category=E. | 0.522 |
ftsL | lolA | Bfl135 | Bfl385 | Cell division protein FtsL; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. | Outer membrane lipoprotein carrier protein precursor; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane). | 0.737 |
ftsL | tolA | Bfl135 | Bfl337 | Cell division protein FtsL; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. | tolA protein; COG category=N. | 0.769 |
ftsL | yccV | Bfl135 | Bfl419 | Cell division protein FtsL; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. | Conserved hypothetical protein; Involved in the degradation of certain denaturated proteins, including DnaA, during heat shock stress; Belongs to the HspQ family. | 0.585 |
ftsL | ygfE | Bfl135 | Bfl258 | Cell division protein FtsL; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. | Cell division protein ZapA; Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division. | 0.771 |
ftsL | yhbN | Bfl135 | Bfl043 | Cell division protein FtsL; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. | OstA-like protein (organic solvent tolerance); COG category=S. | 0.699 |
ftsL | yhcB | Bfl135 | Bfl048 | Cell division protein FtsL; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. | Periplasmic membrane protein associated with membrane transport; COG category=R. | 0.509 |
hemD | ftsL | Bfl581 | Bfl135 | Uroporphyrinogen III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | Cell division protein FtsL; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. | 0.573 |
hemD | ilvM | Bfl581 | Bfl592 | Uroporphyrinogen III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | Acetolactate synthase II, small subunit; COG category=E. | 0.490 |
hemD | tolA | Bfl581 | Bfl337 | Uroporphyrinogen III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | tolA protein; COG category=N. | 0.540 |
hemD | yccV | Bfl581 | Bfl419 | Uroporphyrinogen III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | Conserved hypothetical protein; Involved in the degradation of certain denaturated proteins, including DnaA, during heat shock stress; Belongs to the HspQ family. | 0.694 |
hemD | ygfE | Bfl581 | Bfl258 | Uroporphyrinogen III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | Cell division protein ZapA; Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division. | 0.718 |
hemD | yhcB | Bfl581 | Bfl048 | Uroporphyrinogen III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | Periplasmic membrane protein associated with membrane transport; COG category=R. | 0.666 |
hemD | yjeP | Bfl581 | Bfl073 | Uroporphyrinogen III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | Mechanosensitive ion-channel; COG category=M. | 0.680 |
ilvM | ftsL | Bfl592 | Bfl135 | Acetolactate synthase II, small subunit; COG category=E. | Cell division protein FtsL; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. | 0.522 |
ilvM | hemD | Bfl592 | Bfl581 | Acetolactate synthase II, small subunit; COG category=E. | Uroporphyrinogen III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | 0.490 |
ilvM | lolA | Bfl592 | Bfl385 | Acetolactate synthase II, small subunit; COG category=E. | Outer membrane lipoprotein carrier protein precursor; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane). | 0.653 |
ilvM | minE | Bfl592 | Bfl441 | Acetolactate synthase II, small subunit; COG category=E. | Cell division topological specificity factor; Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell. | 0.717 |
ilvM | tolA | Bfl592 | Bfl337 | Acetolactate synthase II, small subunit; COG category=E. | tolA protein; COG category=N. | 0.577 |