STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ureBUrea amidohydrolase (urease) beta subunit; COG category=E; Belongs to the urease beta subunit family. (103 aa)    
Predicted Functional Partners:
ureC
Urea amidohydrolase (urease) alpha subunit; COG category=E; Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
 0.999
ureA
Urea amidohydrolase (urease) gamma subunit; COG category=E; Belongs to the urease gamma subunit family.
 0.999
ureD
Urease accessory protein D; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
 
 
 0.958
ureF
Urease accessory protein UreF; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
  
 
 0.903
ureG
Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase; Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
  
  
 0.856
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
     
 0.401
Your Current Organism:
Blochmannia floridanus
NCBI taxonomy Id: 203907
Other names: C. Blochmannia floridanus, Candidatus Blochmannia floridanus
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