Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ALX03299.1Derived by automated computational analysis using gene prediction method: Protein Homology. (408 aa)    
Predicted Functional Partners:
ALX03300.1
Hydantoinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.993
ALX03301.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.926
ALX03298.1
Allantoicase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.920
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 0.858
gcvP
Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
  
 
 0.840
ALX03303.1
Aldehyde oxidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.839
ALX03302.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.787
ALX03294.1
glutamyl-tRNA amidotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the amidase family.
 
  0.757
ALX03296.1
5-hydroxyisourate hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.
 
    0.725
ALX06226.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.720
Your Current Organism:
Aeromicrobium erythreum
NCBI taxonomy Id: 2041
Other names: A. erythreum, ATCC 51598, DSM 8599, JCM 8359, LMG 16472, LMG:16472, NBRC 15406, NRRL B-3381
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