ALX03402.1 protein (Aeromicrobium erythreum)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Aeromicrobium erythreum

NCBI taxonomy Id: 2041
Other names: A. erythreum, ATCC 51598, DSM 8599, JCM 8359, LMG 16472, LMG:16472, NBRC 15406, NRRL B-3381

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ALX03400.1	ALX03401.1	AERYTH_01135	AERYTH_01140	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.773
ALX03400.1	ALX03402.1	AERYTH_01135	AERYTH_01145	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.543
ALX03400.1	ALX03403.1	AERYTH_01135	AERYTH_01150	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Inorganic polyphosphate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.427
ALX03400.1	arc	AERYTH_01135	AERYTH_08985	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	ATPase AAA; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis.	0.515
ALX03401.1	ALX03400.1	AERYTH_01140	AERYTH_01135	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.773
ALX03401.1	ALX03402.1	AERYTH_01140	AERYTH_01145	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.543
ALX03401.1	ALX03403.1	AERYTH_01140	AERYTH_01150	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Inorganic polyphosphate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.427
ALX03401.1	arc	AERYTH_01140	AERYTH_08985	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	ATPase AAA; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis.	0.515
ALX03402.1	ALX03400.1	AERYTH_01145	AERYTH_01135	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.543
ALX03402.1	ALX03401.1	AERYTH_01145	AERYTH_01140	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.543
ALX03402.1	ALX03403.1	AERYTH_01145	AERYTH_01150	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Inorganic polyphosphate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.956
ALX03402.1	ALX03460.1	AERYTH_01145	AERYTH_01480	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.582
ALX03402.1	ALX04442.1	AERYTH_01145	AERYTH_06935	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	ADP-ribose pyrophosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.529
ALX03402.1	ALX05146.1	AERYTH_01145	AERYTH_10755	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Cytochrome B561; Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).	0.477
ALX03402.1	ALX05513.1	AERYTH_01145	AERYTH_12805	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.454
ALX03402.1	ALX06224.1	AERYTH_01145	AERYTH_16740	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.503
ALX03402.1	arc	AERYTH_01145	AERYTH_08985	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	ATPase AAA; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis.	0.455
ALX03402.1	ftsH	AERYTH_01145	AERYTH_02840	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Cell division protein FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family.	0.757
ALX03403.1	ALX03400.1	AERYTH_01150	AERYTH_01135	Inorganic polyphosphate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.427
ALX03403.1	ALX03401.1	AERYTH_01150	AERYTH_01140	Inorganic polyphosphate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.427