STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
disADNA integrity scanning protein DisA; Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP likely acts as a signaling molecule that may couple DNA integrity with a cellular process. (358 aa)    
Predicted Functional Partners:
radA
DNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
  
  
 0.968
ALX05929.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.718
ALX04267.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the helicase family. UvrD subfamily.
   
    0.645
ALX04754.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.497
ALX03925.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.492
ALX06186.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.467
ALX03747.1
Glycosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.444
ALX04750.1
Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.440
ALX04538.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.421
ALX03515.1
CarD family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.416
Your Current Organism:
Aeromicrobium erythreum
NCBI taxonomy Id: 2041
Other names: A. erythreum, ATCC 51598, DSM 8599, JCM 8359, LMG 16472, LMG:16472, NBRC 15406, NRRL B-3381
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