STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ALX03995.1uroporphyrinogen-III synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (372 aa)    
Predicted Functional Partners:
hemC
Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
  
 0.982
ALX04769.1
Siroheme synthase CysG; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.980
ALX03994.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.957
ALX03997.1
Nitrite reductase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
 
  
 0.951
ALX03996.1
Nitrite reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.948
hemE
Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
  
 
 0.943
ALX03766.1
uroporphyrin-III methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.936
ALX05840.1
uroporphyrin-III methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.924
ALX04000.1
Nitrate transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.915
ALX03999.1
Nitrite reductase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
 
   
 0.913
Your Current Organism:
Aeromicrobium erythreum
NCBI taxonomy Id: 2041
Other names: A. erythreum, ATCC 51598, DSM 8599, JCM 8359, LMG 16472, LMG:16472, NBRC 15406, NRRL B-3381
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