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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ALX04676.1Carbonic anhydrase; Derived by automated computational analysis using gene prediction method: Protein Homology. (164 aa)    
Predicted Functional Partners:
ALX04678.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.827
ALX04677.1
MFS transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.812
ALX04679.1
DNA topoisomerase IV subunit A; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.759
ALX04733.1
Amino acid adenylation protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.696
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
   
  
 0.623
ALX05590.1
Anhydrase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 
 0.564
ALX05514.1
Fumarate hydratase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
       0.433
Your Current Organism:
Aeromicrobium erythreum
NCBI taxonomy Id: 2041
Other names: A. erythreum, ATCC 51598, DSM 8599, JCM 8359, LMG 16472, LMG:16472, NBRC 15406, NRRL B-3381
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