| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ALX03279.1 | ALX04198.1 | AERYTH_00480 | AERYTH_05530 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Peptidase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.538 |
| ALX03279.1 | arc | AERYTH_00480 | AERYTH_08985 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | ATPase AAA; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. | 0.817 |
| ALX03279.1 | glpK | AERYTH_00480 | AERYTH_08765 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. | 0.718 |
| ALX04198.1 | ALX03279.1 | AERYTH_05530 | AERYTH_00480 | Peptidase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.538 |
| ALX04198.1 | ALX05755.1 | AERYTH_05530 | AERYTH_14155 | Peptidase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.590 |
| ALX04198.1 | arc | AERYTH_05530 | AERYTH_08985 | Peptidase; Derived by automated computational analysis using gene prediction method: Protein Homology. | ATPase AAA; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. | 0.939 |
| ALX04198.1 | glpK | AERYTH_05530 | AERYTH_08765 | Peptidase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. | 0.918 |
| ALX04198.1 | prcA | AERYTH_05530 | AERYTH_08955 | Peptidase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Proteasome subunit alpha; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. Belongs to the peptidase T1A family. | 0.788 |
| ALX04198.1 | prcB | AERYTH_05530 | AERYTH_08960 | Peptidase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Proteasome subunit beta; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. Belongs to the peptidase T1B family. | 0.788 |
| ALX04820.1 | ALX06098.1 | AERYTH_08970 | AERYTH_16030 | Pup deamidase/depupylase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.548 |
| ALX04820.1 | arc | AERYTH_08970 | AERYTH_08985 | Pup deamidase/depupylase; Derived by automated computational analysis using gene prediction method: Protein Homology. | ATPase AAA; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. | 0.920 |
| ALX04820.1 | prcA | AERYTH_08970 | AERYTH_08955 | Pup deamidase/depupylase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Proteasome subunit alpha; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. Belongs to the peptidase T1A family. | 0.823 |
| ALX04820.1 | prcB | AERYTH_08970 | AERYTH_08960 | Pup deamidase/depupylase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Proteasome subunit beta; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. Belongs to the peptidase T1B family. | 0.822 |
| ALX04820.1 | pup | AERYTH_08970 | AERYTH_08965 | Pup deamidase/depupylase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Ubiquitin; Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation. | 0.845 |
| ALX05755.1 | ALX04198.1 | AERYTH_14155 | AERYTH_05530 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Peptidase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.590 |
| ALX05755.1 | arc | AERYTH_14155 | AERYTH_08985 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | ATPase AAA; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. | 0.838 |
| ALX05755.1 | glpK | AERYTH_14155 | AERYTH_08765 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. | 0.718 |
| ALX06098.1 | ALX04820.1 | AERYTH_16030 | AERYTH_08970 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Pup deamidase/depupylase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.548 |
| ALX06098.1 | arc | AERYTH_16030 | AERYTH_08985 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | ATPase AAA; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. | 0.787 |
| ALX06098.1 | pafA | AERYTH_16030 | AERYTH_08940 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Pup--protein ligase; Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side- chain amino group of a substrate lysine. | 0.688 |
