Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ALX04828.1Carboxylate--amine ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (284 aa)    
Predicted Functional Partners:
ALX04827.1
Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
     
 0.838
ALX04829.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.773
rpoZ
DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
 
     0.709
ALX04898.1
Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.515
ALX03639.1
Inosine-5-monophosphate dehydrogenase; Catalyzes the synthesis of xanthosine monophosphateby the NAD+ dependent oxidation of inosine monophosphate;Derived by automated computational analysis using geneprediction method: Protein Homology.
  
     0.514
nucS
Endonuclease; Cleaves both 3' and 5' ssDNA extremities of branched DNA structures; Belongs to the NucS endonuclease family.
  
     0.480
ALX05144.1
Cytochrome C oxidase subunit IV; Part of cytochrome c oxidase, its function is unknown. Belongs to the cytochrome c oxidase bacterial subunit CtaF family.
  
     0.458
ALX04825.1
Hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.435
ALX05140.1
Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.428
ALX04694.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.419
Your Current Organism:
Aeromicrobium erythreum
NCBI taxonomy Id: 2041
Other names: A. erythreum, ATCC 51598, DSM 8599, JCM 8359, LMG 16472, LMG:16472, NBRC 15406, NRRL B-3381
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