node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ALX04870.1 | ALX04871.1 | AERYTH_09250 | AERYTH_09255 | Iron ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Phosphoserine phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.701 |
ALX04871.1 | ALX04870.1 | AERYTH_09255 | AERYTH_09250 | Phosphoserine phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Iron ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.701 |
ALX04871.1 | ALX05035.1 | AERYTH_09255 | AERYTH_10140 | Phosphoserine phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Cystathionine beta-synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.947 |
ALX04871.1 | ALX05308.1 | AERYTH_09255 | AERYTH_11655 | Phosphoserine phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.751 |
ALX04871.1 | ALX05529.1 | AERYTH_09255 | AERYTH_12895 | Phosphoserine phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Threonine dehydratase; Catalyzes the formation of 2-oxobutanoate from L-threonine; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.909 |
ALX04871.1 | glyA | AERYTH_09255 | AERYTH_00220 | Phosphoserine phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.949 |
ALX04871.1 | ilvA | AERYTH_09255 | AERYTH_02880 | Phosphoserine phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | 0.909 |
ALX04871.1 | metXA | AERYTH_09255 | AERYTH_00270 | Phosphoserine phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Homoserine acetyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine. | 0.831 |
ALX04871.1 | serC | AERYTH_09255 | AERYTH_13220 | Phosphoserine phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. | 0.980 |
ALX04871.1 | trpA | AERYTH_09255 | AERYTH_10345 | Phosphoserine phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Tryptophan synthase subunit alpha; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.903 |
ALX04871.1 | trpB | AERYTH_09255 | AERYTH_10350 | Phosphoserine phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Tryptophan synthase subunit beta; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.921 |
ALX05035.1 | ALX04871.1 | AERYTH_10140 | AERYTH_09255 | Cystathionine beta-synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Phosphoserine phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.947 |
ALX05035.1 | ALX05308.1 | AERYTH_10140 | AERYTH_11655 | Cystathionine beta-synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.410 |
ALX05035.1 | ALX05529.1 | AERYTH_10140 | AERYTH_12895 | Cystathionine beta-synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Threonine dehydratase; Catalyzes the formation of 2-oxobutanoate from L-threonine; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.921 |
ALX05035.1 | glyA | AERYTH_10140 | AERYTH_00220 | Cystathionine beta-synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.942 |
ALX05035.1 | ilvA | AERYTH_10140 | AERYTH_02880 | Cystathionine beta-synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | 0.921 |
ALX05035.1 | metXA | AERYTH_10140 | AERYTH_00270 | Cystathionine beta-synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Homoserine acetyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine. | 0.854 |
ALX05035.1 | trpA | AERYTH_10140 | AERYTH_10345 | Cystathionine beta-synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Tryptophan synthase subunit alpha; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.916 |
ALX05035.1 | trpB | AERYTH_10140 | AERYTH_10350 | Cystathionine beta-synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Tryptophan synthase subunit beta; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.908 |
ALX05308.1 | ALX04871.1 | AERYTH_11655 | AERYTH_09255 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Phosphoserine phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.751 |