leuA protein (Aeromicrobium erythreum) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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co-expression

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gene co-occurrence

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Your Current Organism:

Aeromicrobium erythreum

NCBI taxonomy Id: 2041
Other names: A. erythreum, ATCC 51598, DSM 8599, JCM 8359, LMG 16472, LMG:16472, NBRC 15406, NRRL B-3381

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ALX03555.1	ALX04079.1	AERYTH_02005	AERYTH_04890	acetyl-CoA acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family.	acetyl-COA carboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.922
ALX03555.1	ALX06146.1	AERYTH_02005	AERYTH_16295	acetyl-CoA acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.922
ALX03555.1	leuA	AERYTH_02005	AERYTH_11490	acetyl-CoA acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family.	2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.	0.923
ALX04079.1	ALX03555.1	AERYTH_04890	AERYTH_02005	acetyl-COA carboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology.	acetyl-CoA acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family.	0.922
ALX04079.1	ALX06146.1	AERYTH_04890	AERYTH_16295	acetyl-COA carboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.915
ALX04079.1	leuA	AERYTH_04890	AERYTH_11490	acetyl-COA carboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology.	2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.	0.938
ALX04462.1	ALX04463.1	AERYTH_07040	AERYTH_07045	Acetolactate synthase large subunit; catalyzes the formation of 2-acetolactate from pyruvate; Derived by automated computational analysis using gene prediction method: Protein Homology.	Acetolactate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.999
ALX04462.1	ALX04473.1	AERYTH_07040	AERYTH_07095	Acetolactate synthase large subunit; catalyzes the formation of 2-acetolactate from pyruvate; Derived by automated computational analysis using gene prediction method: Protein Homology.	Catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.605
ALX04462.1	ALX05009.1	AERYTH_07040	AERYTH_09985	Acetolactate synthase large subunit; catalyzes the formation of 2-acetolactate from pyruvate; Derived by automated computational analysis using gene prediction method: Protein Homology.	Class IV aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.471
ALX04462.1	ilvD	AERYTH_07040	AERYTH_07030	Acetolactate synthase large subunit; catalyzes the formation of 2-acetolactate from pyruvate; Derived by automated computational analysis using gene prediction method: Protein Homology.	Dihydroxy-acid dehydratase; Catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the IlvD/Edd family.	0.972
ALX04462.1	leuA	AERYTH_07040	AERYTH_11490	Acetolactate synthase large subunit; catalyzes the formation of 2-acetolactate from pyruvate; Derived by automated computational analysis using gene prediction method: Protein Homology.	2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.	0.927
ALX04462.1	leuC	AERYTH_07040	AERYTH_11365	Acetolactate synthase large subunit; catalyzes the formation of 2-acetolactate from pyruvate; Derived by automated computational analysis using gene prediction method: Protein Homology.	Isopropylmalate isomerase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.	0.716
ALX04462.1	leuD	AERYTH_07040	AERYTH_11360	Acetolactate synthase large subunit; catalyzes the formation of 2-acetolactate from pyruvate; Derived by automated computational analysis using gene prediction method: Protein Homology.	Isopropylmalate isomerase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily.	0.706
ALX04463.1	ALX04462.1	AERYTH_07045	AERYTH_07040	Acetolactate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Acetolactate synthase large subunit; catalyzes the formation of 2-acetolactate from pyruvate; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.999
ALX04463.1	ALX04473.1	AERYTH_07045	AERYTH_07095	Acetolactate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.666
ALX04463.1	ALX05009.1	AERYTH_07045	AERYTH_09985	Acetolactate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Class IV aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.518
ALX04463.1	ilvD	AERYTH_07045	AERYTH_07030	Acetolactate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Dihydroxy-acid dehydratase; Catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the IlvD/Edd family.	0.949
ALX04463.1	leuA	AERYTH_07045	AERYTH_11490	Acetolactate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.	0.954
ALX04463.1	leuC	AERYTH_07045	AERYTH_11365	Acetolactate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Isopropylmalate isomerase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.	0.857
ALX04463.1	leuD	AERYTH_07045	AERYTH_11360	Acetolactate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Isopropylmalate isomerase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily.	0.881