STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nthEndonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. (207 aa)    
Predicted Functional Partners:
C824_01935
Exodeoxyribonuclease III (Xth).
 
 0.993
rnfE
Ion-translocating oxidoreductase complex subunit E; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
 
  
 0.846
ung
Uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
  
 0.702
C824_00619
PfkB domain-containing protein.
       0.647
nfo
Probable endonuclease 4; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin.
  
 
 0.631
rnfG
Ion-translocating oxidoreductase complex subunit G; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the RnfG family.
  
  
 0.627
C824_00620
PadR family transcriptional regulator.
       0.579
C824_00621
Uncharacterized protein.
       0.573
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
  
 
 0.567
sfsA
Sugar fermentation stimulation protein homolog; Belongs to the SfsA family.
 
 
0.532
Your Current Organism:
Schaedlerella arabinosiphila
NCBI taxonomy Id: 2044587
Other names: Clostridiaceae bacterium DSM 106076, Clostridiales bacterium TLL-A1, Clostridium sp. ASF502, DSM 106076, KCTC 15657, S. arabinosiphila, Schaedlerella arabinosiphila Soh et al. 2019, personal::TLL-A1T, strain TLL-A1T
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