Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AIY19815.2RNA polymerase sigma-70 factor; Belongs to the sigma-70 factor family. ECF subfamily. (213 aa)    
Predicted Functional Partners:
AJR18275.1
Hypothetical protein.
  
 
 0.863
rpoB
DNA-directed RNA polymerase beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.852
rpoC
DNA-directed RNA polymerase beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.852
AIY18784.1
CarD-like transcriptional regulator.
   
 
 0.848
AIY16075.1
RNA polymerase ECF-type sigma factor; Belongs to the sigma-70 factor family. ECF subfamily.
  
     0.756
rpoZ
DNA-directed RNA polymerase omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
    
 
 0.741
rpoA
DNA-directed RNA polymerase alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.741
AIY16575.1
Putative ECF sigma factor; Belongs to the sigma-70 factor family. ECF subfamily.
  
     0.739
AIY16263.1
Putative RNA polymerase sigma factor; Belongs to the sigma-70 factor family. ECF subfamily.
  
     0.733
AIY17863.1
RNA polymerase ECF sigma factor; Belongs to the sigma-70 factor family. ECF subfamily.
  
     0.720
Your Current Organism:
Pimelobacter simplex
NCBI taxonomy Id: 2045
Other names: ATCC 6946, Arthrobacter simplex, CCUG 23611, CIP 82.106, Corynebacterium simplex, DSM 20130, HAMBI 90, IFO 12069, KCTC 9106, LMG 16261, LMG:16261, NBRC 12069, NCIB 8929, NCIB:8929, Nocardioides simplex, P. simplex
Server load: low (24%) [HD]